Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source

by Magalie Bondu, Manuel J. Marques, P.M. Moselund, G. Lall, Adrian Bradu, and Adrian Podoleanu

Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source, Photoacoustics 9, 21-30 (2018).

In this paper we report on the use of a single supercontinuum (SC) source for multimodal imaging. The 2-octave bandwidth (475-2300 nm) makes the SC source suitable for optical coherence tomography (OCT) as well as for multispectral photoacoustic microscopy (MPAM). The IR band centered at 1310 nm is chosen for OCT to penetrate deeper into tissue with 8 mW average power on the sample. The 500-840 nm band is used for MPAM. The source has the ability to select the central wavelength as well as the spectral bandwidth. An energy of more than 35 nJ within a less than 50 nm bandwidth is achieved on the sample for wavelengths longer than 500 nm. In the present paper, we demonstrate the capabilities of such a multimodality imaging instrument based on a single optical source. In-vitro mouse ear B-scan images are presented.